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What federal office is responsible for enforcing HIPAA? The Health Insurance Portability and Accountability Act (HIPAA) is a crucial piece of legislation in the United States that protects sensitive patient information. Ensuring compliance with HIPAA regulations is essential for healthcare providers, insurance companies, and any entity that handles protected health information (PHI). But who enforces these regulations and ensures that they are followed? Let’s delve into the federal office responsible for enforcing HIPAA and the role it plays in safeguarding patient privacy.